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業績詳細

業績項目 学術雑誌論文(学内)
タイトル・書名 Acute Fulminant Necrotizing Amebic Colitis and Enterocolitis Associated with Perforation in a Male Breast Cancer Patient
著者
学部・講座・部門
施設
UMEMOTO Takahiro
2018  年度
医学部 外科学 消化器一般外科学
2018  年度
藤が丘病院
著者
学部・講座・部門
施設
OHIKE Nobuyuki
2018  年度
医学部 臨床病理診断学 部門なし
2018  年度
藤が丘病院
著者
学部・講座・部門
施設
SEKINE Ryuichi
2018  年度
医学部 外科学 消化器一般外科学
2018  年度
藤が丘病院
著者
学部・講座・部門
施設
HARADA Yoshikuni
2018  年度
医学部 外科学 消化器一般外科学
2018  年度
藤が丘病院
著者
学部・講座・部門
施設
AOKI Takeshi
2018  年度
医学部 外科学 消化器一般外科学
2018  年度
藤が丘病院
著者
学部・講座・部門
施設
TANAKA Jun-ichi
2018  年度
医学部 外科学 消化器一般外科学
2018  年度
藤が丘病院
雑誌名 Showa Univ J Med Sci
巻・号 30 巻      3 号
開始・終了ページ 開始 391  ページ /  終了  396  ページ
刊行年月 2018 年 09 月
言語 英語
内容記述 In Japan, amebiasis is typically found in men who have sex with men and in individuals with recent travel to endemic areas. We experienced a patient with fulminant necrotizing amebic colitis and enterocolitis who presented with a severe disorder of the liver and renal function. The patient was a 71-year-old man who had lived in Yokohama City, Japan for 30 years. His stool sample showed no amebic dysentery protozoa and cultured negatively for human immunodeficiency virus. Despite being treated with meropenem, pyrexia of 39-40°C continued for 4 days. On hospital day 8, a colonic abscess and perforation of the transverse colon were detected by computed tomography(CT). His fever did not improve, suggesting progression of infectious disease. Subsequent emergency laparotomy revealed a perforation in the middle of the transverse colon. Peritoneal lavage and right hemicolectomy were performed; however, a CT scan on hospital day 16 (postoperative day 8) showed re-perforation of the colon and an abscess around the site of anastomosis, prompting emergency intestinal and left hemicolectomy resection. Amebae observed pathologically during the second emergency operation led to a diagnosis of amebic colitis. Endotoxin adsorption therapy was performed, and metronidazole was administered. Despite prompt diagnosis and treatments, the patient’s general conditions became fulminant, and multiple organ failure developed. On hospital day 18 (postoperative day 10), his C-reactive protein level was 20mg/dl. He was clinically diagnosed as having sepsis and multiple organ failure. The patient died on hospital day 23. Acute colitis is commonly encountered in daily practice, but it is difficult to differentiate between amebic and non-amebic colitis preoperatively and thus, the possibility of amebic colitis should be considered in such clinical presentations.
出版者 Showa University Society
ISSN 0915-6380
資源識別子URI http://researchers-achievements.showa-u.ac.jp/dispGyoseki/?item_id=1033869&item_no=1
査読 あり
論文種別 症例報告