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業績項目 学術雑誌論文(学内)
タイトル・書名 Satisfaction with Decision Regarding BRCA1/2 Genetic Testing and Willingness to Undergo BRCA1/2 Genetic Testing in the Future Among Breast Cancer Patients who Had not Previously Undergone BRCA1/2 Genetic Testing in Japan
著者
学部・講座・部門
施設
INUZUKA Mayuko
2017  年度
医学部 外科学 乳腺外科学
2017  年度
昭和大学病院・東病院
著者
学部・講座・部門
施設
KUWAYAMA Takashi
2017  年度
医学部 外科学 乳腺外科学
2017  年度
昭和大学病院・東病院
著者
学部・講座・部門
施設
SAWADA Terumasa
2017  年度
医学部 外科学 乳腺外科学
2017  年度
昭和大学病院・東病院
著者
学部・講座・部門
施設
AKASHI-TANAKA Sadako
2017  年度
医学部 外科学 乳腺外科学
2017  年度
昭和大学病院・東病院
著者
学部・講座・部門
施設
NAKAMURA Seigo
2017  年度
医学部 外科学 乳腺外科学
2017  年度
昭和大学病院・東病院
雑誌名 Showa Univ J Med Sci
巻・号 30 巻      1 号
開始・終了ページ 開始 87  ページ /  終了  96  ページ
刊行年月 2018 年 03 月
言語 英語
内容記述 Breast cancer patients must make their own decision of whether or not to undergo BRCA1/2 genetic testing. The present study investigated satisfaction surrounding this decision and the willingness to undergo BRCA1/2 genetic testing in the future among breast cancer patients who had not previously undergone BRCA1/2 testing despite a family history of breast cancer. Consent was obtained from 103 eligible patients selected from breast cancer patients who had presented with suspected hereditary breast and ovarian cancer and attended genetic counseling sessions at our institution. Consenting patients were then asked to complete a survey by questionnaire. Irrespective of their decision to undergo BRCA1/2 genetic testing, no patient reported being “not satisfied at all” or “not very satisfied”. Among the patients opting to not undergo BRCA1/2 genetic testing, 64% responded that they would like to undergo BRCA1/2 genetic testing in the future. Compared with the patients who did not want to undergo testing, those who wanted to undergo were more likely to harbor impressions that BRCA1/2 genetic testing is “conducive to the selection of therapeutic modalities”, “helpful in deciding whether to undergo prophylactic surgery (oophorectomy, salpingectomy, and mastectomy)”, and “expensive”. Genetic counseling can improve satisfaction regarding the decision to undergo or not undergo BRCA1/2 genetic testing. However, there were some patients who opted not to undergo testing, but they were willing to undergo BRCA1/2 genetic testing in the future. Many of these patients might have found it cost-prohibitive to undergo testing immediately, despite realizing its benefits.
出版者 Showa University Society
ISSN 0915-6380
資源識別子URI http://researchers-achievements.showa-u.ac.jp/dispGyoseki/?item_id=1029775&item_no=1
査読 あり
論文種別 原著